Mannotriose induced differentiation of mesenchymal stem cells into neuron-like cells
نویسندگان
چکیده
This article demonstrates that mannotriose effectively induces the differentiation of mesenchymal stem cells into neuron-like in vitro. Rat-derived were investigated on their potential to differentiate induced by purified from Radix Rehmanniae Preparata The percentage neuron-specific enolase positive and Nissl after treatment was increased. mRNA levels neurofilament medium upregulated group compared control. These findings demonstrate can induce rat-derived cells.
منابع مشابه
Harvesting of bone marrow mesenchymal stem cells from live rats and the in vitro differentiation of bone marrow mesenchymal stem cells into neuron-like cells
In the bone marrow, there are certain populations of stem cell sources with the capacity to differentiate into several different types of cells. Ideally, cell transplants would be readily obtainable, easy to expand and bank, and capable of surviving for sufficient periods of time. Bone marrow mesenchymal stem cells (BM-MSCs) possess all of these characteristics. One of the most important benefi...
متن کاملDifferentiation of Umbilical Cord Lining Membrane-Derived Mesenchymal Stem Cells into Endothelial-Like Cells
Background: Stem cell therapy for the treatment of vascular-related diseases through functional revascularization is one of the most important research areas in tissue engineering. The aim of this study was to investigate the in vitro differentiation of umbilical CL-MSC into endothelial lineage cells. Methods: In this study, isolated cells were characterized for expression of MSC-specific marke...
متن کاملTrans-differentiation of the Adipose Tissue-Derived Stem Cells into Neuron-Like Cells Expressing Neurotrophins by Selegiline
Background: Adult stem cells (ASC) are undifferentiated cells found throughout the body. These cells are promising tools for cell replacement therapy in neurodegenerative disease. Adipose tissue is the most abundant and accessible source of ASC. This study was conducted to evaluate effect of selegiline on differentiation of adipose-derived stem cells (ADSC) into functional neuron-like cells (NL...
متن کاملEffect of let-7a overexpression on the differentiation of conjunctiva mesenchymal stem cells into photoreceptor-like cells
Objective(s): MicroRNAs (miRNAs) could regulate many cellular processes such as proliferation and differentiation. let-7a miRNA is one of the key regulators in the developmental transition of retinal progenitor cells into differentiated cells. Current evidence suggests that mesenchymal stem cells (MSCs) can isolate from various tissues such as bone marrow and conjuncti...
متن کاملharvesting of bone marrow mesenchymal stem cells from live rats and the in vitro differentiation of bone marrow mesenchymal stem cells into neuron-like cells
in the bone marrow, there are certain populations of stem cell sources with the capacity to differentiate into several different types of cells. ideally, cell transplants would be readily obtainable, easy to expand and bank, and capable of surviving for sufficient periods of time. bone marrow mesenchymal stem cells (bm-mscs) possess all of these characteristics. one of the most important benefi...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of Integrative Neuroscience
سال: 2021
ISSN: ['1757-448X', '0219-6352']
DOI: https://doi.org/10.31083/j.jin.2021.01.214